The Republican-controlled Senate narrowly passed President Donald Trump’s sweeping domestic policy package Tuesday morning, bringing it one step closer to his desk.

The 51-50 vote followed a marathon overnight session that spanned more than 24 hours, during which senators voted on dozens of proposed changes to the legislation and GOP leaders dragged out many of the votes as they frantically worked to win over holdouts. They ultimately secured enough votes with a catch-all amendment that was approved by a vote of 51-50 with Vice President JD Vance voting to break the tie.

Voting against the final bill, alongside all 47 Democrats, were Republican Sens. Rand Paul of Kentucky, Thom Tillis of North Carolina and Susan Collins of Maine.

Tuesday’s vote puts Trump on the cusp of a major legislative victory and hands Senate Majority Leader John Thune, R-S.D., the biggest win of his first six months on the job.